Anti-ABCA7 Antibody

Raised in rabbit against the ABCA7 transporter, this polyclonal reagent targets a membrane-associated ATP-binding cassette protein involved in cellular lipid homeostasis and phagocytic clearance. Genome-wide association studies have connected ABCA7 variants to altered susceptibility to late-onset Alzheimer's disease, making antibodies against this target useful for laboratories investigating neurodegeneration, lipid trafficking, and innate immune function in microglial and macrophage populations.

Validated for western blot and immunohistochemistry workflows, the reagent detects the protein in human, mouse, and rat samples, enabling cross-species comparisons in neural and peripheral tissues. The unconjugated preparation, supplied at 1 mg/ml in phosphate buffered saline with 0.05% sodium azide at approximately pH 7.3, allows flexible pairing with user-selected secondary labels and detection chemistries.

Provided by Antibodies.com as 100 µl of liquid stock, this Primary Antibodies reagent is suited to immunoblotting of cell and tissue lysates, IHC staining of fixed sections, and complementary antibody-based detection methods where a polyclonal recognition profile is advantageous.