Anti-ABCA6 Antibody

ABCA6 (ATP-binding cassette transporter A6) belongs to the ABCA subfamily of membrane transporters implicated in lipid and sterol homeostasis across tissues such as liver, brain and macrophages. This rabbit-derived reagent from Antibodies.com is supplied as an unconjugated polyclonal antiserum in a 100 µl volume, raised against the ABCA6 target and validated for Western blot and immunohistochemistry workflows on human, mouse and rat samples.

The antibody is formatted as a ready-to-titer liquid in a vial and arrives frozen for storage at -20 °C; aliquoting on first thaw is recommended to limit freeze-thaw cycles and preserve reactivity over time. It performs cleanly on whole-cell lysates and on formalin-fixed, paraffin-embedded sections, producing a band of the expected molecular weight for ABCA6 in immunoblots and a membranous and cytoplasmic staining pattern in IHC, consistent with the protein's localization at the plasma membrane and within intracellular vesicular compartments.

Because the reagent is unconjugated, researchers can couple it to HRP, biotin, fluorophores or gold depending on the assay, and the polyclonal host allows recognition of multiple epitopes on the transporter for more tolerant detection across human, mouse and rat samples. For research use only.