Anti-ABCA4 Antibody

ABCA4 is an ATP-binding cassette transporter found in the disc membranes of retinal photoreceptor cells. It helps remove retinoid compounds generated during light exposure, making the protein relevant to studies of visual-cycle transport, photoreceptor homeostasis, and retinal disease mechanisms.

The 200 µl antibody is a rabbit IgG polyclonal, unconjugated reagent for western blot and immunofluorescence. The listed reactive species are Human, Mouse, and Rat, supporting comparative studies of ABCA4 expression and localization in cell and tissue research samples. Its unconjugated format allows researchers to select compatible labeled secondary antibodies and detection systems.

ABCA4 mutations are associated with Stargardt disease and cone-rod dystrophy. The antibody is therefore useful for examining normal protein distribution, altered expression in retinal disease models, and subcellular localization by fluorescence microscopy. Antibodies.com supplies this primary antibody for laboratory investigation of retinal biology and related protein-function pathways.