Anti-AARS2 Antibody

This rabbit polyclonal primary antibody from Antibodies.com targets AARS2, the nuclear-encoded mitochondrial alanyl-tRNA synthetase that catalyzes the attachment of alanine to its cognate mitochondrial tRNA during organellar protein synthesis. The unconjugated reagent is supplied as a 100 µl aliquot and is validated for western blot and immunohistochemistry on human and mouse samples, supporting investigation of combined oxidative phosphorylation deficiency, leukoencephalopathy with thalamus and brainstem involvement, and premature ovarian insufficiency phenotypes linked to AARS2 dysfunction. Because AARS2 localizes to the mitochondrial matrix, researchers commonly pair this reagent with fractionation or enrichment protocols when probing tissue-specific expression or characterizing patient-derived fibroblasts.