Anti-a-Synuclein (Ab-133) Antibody

Alpha-Synuclein phosphorylation research depends on antibodies that distinguish the modified protein from the unmodified pool, and this polyclonal reagent from Antibodies.com targets the Ab-133 epitope implicated in Lewy body pathology and Parkinson's disease progression. The antibody is validated for Western Blot and Immunofluorescence, supporting both immunoblot detection of phosphorylated alpha-synuclein species in brain lysates and subcellular imaging of aggregates in dopaminergic neurons and tissue sections.

Confirmed reactivity covers human, mouse, and rat samples, enabling cross-species studies in transgenic rodent models, primary neuron cultures, and human post-mortem tissue. Supplied as 100 µl of unconjugated rabbit polyclonal antiserum, the reagent accommodates downstream labelling with fluorophores, HRP, or biotin depending on assay design. Storage at -20°C with aliquoting after receipt preserves reactivity across repeated freeze-thaw cycles, and brief centrifugation before first use recovers full volume from the vial.