Anti-A Cyclase IX Antibody

Produced in rabbit as a polyclonal reagent, this unconjugated primary antibody targets adenylate cyclase IX (ADCY9), a membrane-bound enzyme that catalyzes the conversion of ATP into cyclic AMP and that is distinguished from most other adenylate cyclase isoforms by its relative insensitivity to forskolin stimulation. Distributed by Antibodies.com as a 100 µl aliquot, the antibody is validated for western blot, immunohistochemistry, and ELISA workflows on human samples, where it recognizes the endogenous ADCY9 polypeptide in cell and tissue lysates. Researchers investigating G protein-coupled receptor signaling, cAMP-mediated second messenger pathways, and isoform-specific contributions to calcium handling routinely use this reagent to map ADCY9 expression across tissues. Its documented relevance to asthma susceptibility and to pharmacogenomic responses, including altered bronchodilator reactivity, also makes the antibody a useful tool for respiratory and cardiovascular signal-transduction studies.