Anti-5-HT-4 Antibody

Generated in rabbit and affinity-purified as a polyclonal reagent, this unconjugated primary antibody from Antibodies.com binds the human 5-HT-4 (5-hydroxytryptamine receptor 4) G-protein coupled receptor. The 100 µl aliquot is supplied as an unconjugated preparation ready for western blot and immunofluorescence workflows, where it labels the receptor in transfected cell lines and in tissue sections expressing the native human protein.

5-HT-4 receptors are widely studied in gastrointestinal motility research, central nervous system signaling related to learning and memory, and in cardiac and endocrine tissues. Researchers use antibodies such as this one to map receptor distribution, track agonist- or antagonist-induced changes in expression, and to support translational work on serotonergic drug targets for conditions including Alzheimer's disease, depression-like behavior, and irritable bowel syndrome models.

Validated applications on the product sheet are western blot (WB) and immunofluorescence (IF) on human samples. The host species is rabbit, clonality is polyclonal, and the conjugate is unconjugated, allowing flexible pairing with HRP-, fluorophore-, or biotin-labeled secondary reagents in either workflow. The 100 µl volume is sufficient for multiple standard immunoblots or imaging runs depending on dilution.