Anti-4E-BP1 (Ab-45) Antibody

Targeting the translational repressor 4E-BP1, this rabbit polyclonal reagent from Antibodies.com recognizes an epitope near residue 45 of the protein and supports research into mTORC1 signaling, cap-dependent translation initiation, and downstream cell growth responses.

The antibody is validated for western blot, immunohistochemistry, and immunofluorescence applications and reacts with human, mouse, and rat samples. Supplied as a 100 µl unconjugated vial, the polyclonal reagent offers broad epitope coverage and can be paired with labeled secondary reagents for chromogenic or fluorescence detection.

Researchers use 4E-BP1 antibodies to monitor phosphorylation changes following insulin stimulation, nutrient deprivation, or rapamycin treatment, and to investigate pathway dysregulation in cancer, metabolic disease, and neurobiology. The unconjugated format and broad species reactivity make the reagent practical for both standard and exploratory workflows in signaling research.