Anti-4E-BP1 (Ab-36) Antibody

Targeting the threonine 36 phospho-site of 4E-BP1, this unconjugated rabbit polyclonal reagent from Antibodies.com supports research into mTORC1-driven translational control. 4E-BP1 (eIF4E-binding protein 1, also called PHAS-I) binds eIF4E and represses cap-dependent translation initiation until phosphorylated by mTOR; the T36 site is one of the priming residues in that regulatory cascade. The antibody is supplied as a 100 µL vial and has been validated for western blot (WB) analysis of cell lysates and for immunohistochemistry (IHC) staining of tissue sections, with reactivity confirmed in human, mouse, and rat samples. Use it to monitor mTOR pathway activity, study growth-factor and nutrient signalling, or probe translation dysregulation in cancer and metabolic-disease models. Store aliquots at -20 °C and avoid repeated freeze-thaw cycles to preserve phospho-specific binding.