Anti-40S ribosomal protein S11 Antibody

The 40S ribosomal protein S11 (RPS11) is an approximately 18 kDa core component of the small ribosomal subunit, encoded on chromosome 19 and catalogued as UniProt P62280. This polyclonal antibody from Antibodies.com provides a specific detection reagent for RPS11, raised in rabbit and supplied as 100 µg of unconjugated IgG for use in Western blot and immunohistochemistry on human samples.

Within the ribosome, RPS11 contributes to the structural assembly of the 40S subunit and has been studied in the context of translation regulation, ribosomal stress responses, and ribosomal protein haploinsufficiency syndromes. Researchers investigating ribosome biogenesis, translational control, or the contribution of individual ribosomal proteins to cellular proliferation can use this reagent to monitor endogenous RPS11 levels in cell lysates and tissue sections.

The unconjugated format allows flexible pairing with user-selected secondary antibodies, supporting both chromogenic and fluorescence-based detection. For western blotting, the antibody enables assessment of RPS11 expression across cultured cell lines and primary tissues, while the immunohistochemistry application supports localization studies in formalin-fixed paraffin-embedded specimens. Store refrigerated and aliquot upon receipt to limit freeze-thaw cycles; working aliquots may be frozen for longer-term storage.