Anti-3β-HSD7 Antibody

Raised in rabbit against the 3β-hydroxysteroid dehydrogenase type 7 (3β-HSD7) enzyme, this unconjugated polyclonal antibody from Antibodies.com supports studies of bile acid biosynthesis and steroid metabolism. The reagent is validated for Western blot and ELISA workflows and reacts with human, mouse, and rat samples, enabling cross-species comparison of hepatic, adrenal, and placental tissue lysates. Provided in a 100 µl vial, the antibody supplies enough material for multiple immunoblot membranes and microplate assays.

3β-HSD7 catalyzes the C-3 oxidation step in the alternative pathway that converts cholesterol into chenodeoxycholic acid, and laboratories investigating neonatal cholestasis, inborn errors of bile acid synthesis, or peroxisomal dysfunction routinely probe enzyme expression in patient biopsies and knockout models with this reagent. For best results, store aliquots at -20 °C and avoid repeated freeze-thaw cycles that can erode polyclonal reactivity. Each preparation is affinity-purified and intended for research use only.