Anti-20S Proteasome alpha6 Antibody

This rabbit polyclonal antibody from Antibodies.com targets the alpha6 subunit (PSMA1) of the 20S proteasome core particle, a central component of the ubiquitin-dependent protein degradation pathway. Supplied as 100 µl of unconjugated polyclonal antiserum raised in rabbit, the reagent is reactive with human samples and validated for Western blot, immunohistochemistry, and immunofluorescence workflows. Alpha6 contributes to assembly of the outer alpha-ring of the proteasome and regulates gate opening into the catalytic 20S chamber, making it a useful marker for studies of proteasome composition, protein homeostasis, and disease models in cancer biology and neurodegeneration research.