Anti-20S Proteasome alpha2 Antibody

PSMA2 is one of seven α-type subunits that form the outer rings of the 20S proteasome core particle, the catalytic centerpiece of ubiquitin-dependent protein degradation in eukaryotic cells. This unconjugated polyclonal reagent from Antibodies.com, raised in rabbit, is supplied as a 100 µl volume and validated for Western blot, immunohistochemistry, and immunofluorescence applications on human samples. The polyclonal format recognizes multiple epitopes on the target, supporting robust signal across denaturing and native detection conditions. On SDS-PAGE, the alpha2 subunit migrates near 26 kDa, providing a useful reference band when probing whole-cell or nuclear extracts for proteasome content. Because 20S assembly dynamics and proteasome activity shape antigen presentation, cell-cycle progression, and the cellular stress response, this reagent is well suited to proteostasis research, neurodegeneration models, and oncology studies that examine proteasome subunit composition. The unconjugated format also makes it straightforward to pair with secondary detection reagents or custom labeling strategies of the researcher's choice.