Anti-14-3-3 protein beta / alpha Antibody

This rabbit polyclonal antibody targets the 14-3-3 protein beta/alpha isoform, a ~28 kDa adapter protein encoded by the YWHAB gene that binds phosphorylated serine and threonine residues on a wide range of client proteins. Manufactured by Antibodies.com as an unconjugated IgG reagent, it is supplied at 100 µg per vial and is validated for western blot and immunohistochemistry workflows. The reagent has been confirmed reactive with Human, Mouse, and Rat samples, supporting translational studies from rodent disease models to human tissue specimens. Researchers studying cell signalling, apoptosis regulation, neurobiology, and the use of 14-3-3 as a cerebrospinal fluid biomarker in prion disease and traumatic brain injury routinely deploy this reagent to map isoform-specific expression and post-translational modifications. The polyclonal format improves tolerance for minor sequence variation between species and between the closely related beta and alpha isoforms, supporting reproducible detection in both denatured (WB) and fixed-tissue (IHC) preparations. Store refrigerated and protect from light; aliquot to limit freeze-thaw cycles. For research use only.