Anti-14-3-3 beta Antibody

This unconjugated rabbit polyclonal reagent from Antibodies.com targets the 14-3-3 beta regulatory protein (YWHAB), a 28 kDa adapter molecule implicated in cell-cycle progression, apoptosis signalling, and neuronal survival pathways. The antibody is supplied as 100 µl of liquid stock and is validated for Western blot, immunohistochemistry, and immunofluorescence workflows on human samples, where it typically recognizes a band near 28 kDa in lysates of brain, liver, and HeLa origin.

Raised in rabbit and affinity purified, the polyclonal format gives broad epitope coverage for detecting endogenous 14-3-3 beta in fixed tissue sections and cultured cells. The unconjugated preparation allows direct labelling with fluorophores, biotin, or HRP depending on the experimental need, and the reagent has been used in published studies examining 14-3-3 isoform expression in neurodegenerative disease research and signal transduction investigations.

Storage at 4 °C is recommended for short-term use, with aliquoting advised to limit freeze-thaw cycles and preserve antibody titre across repeated experiments.