Anti-14-3-3 ε Antibody

The 14-3-3 ε (YWHAE) protein is a highly conserved adapter molecule implicated in neuronal migration, cortical development, and cell-cycle checkpoint signaling. Heterozygous deletions of the YWHAE locus at 17p13.3 have been associated with Miller-Dieker syndrome, making this isoform a frequent target of active neuroscience research.

This polyclonal reagent from Antibodies.com is raised in rabbit and supplied as 100 µl of unconjugated antiserum. Validated applications include Western blot, immunohistochemistry, immunofluorescence, and ELISA across human, mouse, and rat samples. The unconjugated format allows flexible pairing with custom secondary labels of the researcher's choosing.

Aliquot the antiserum upon first use to limit freeze-thaw cycles; refrigerate for short-term storage and keep frozen for longer-term stability. Each vial is intended for research use only as a single-use or low-repeat reagent suitable for detection of the epsilon isoform in brain, neuronal, and broader tissue lysates.