Anti-11β-HSD1 Antibody

Produced by Antibodies.com as a research-grade primary antibody, this rabbit polyclonal reagent targets 11β-HSD1 (11β-hydroxysteroid dehydrogenase type 1), an enzyme involved in glucocorticoid metabolism that has been implicated in metabolic syndrome, obesity, and inflammatory research. The antibody was raised against a synthetic peptide derived from the N-terminal region of human 11β-HSD1 and affinity-purified from rabbit antiserum by epitope-specific immunogen chromatography, ensuring selective recognition of endogenous11β-HSD1 protein. Supplied as a 50 µl liquid formulation in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide at a working concentration of 1 mg/ml, the unconjugated IgG is intended for use in Western blotting (WB), immunohistochemistry (IHC) and ELISA workflows. Cross-reactivity has been validated against human, mouse and rat samples, making it suitable for translational studies that span rodent models and human tissue. For optimal preservation of activity, vials should be stored at –20 °C, where the reagent remains stable for up to one year. Researchers investigating HSD11B1 expression in hepatic, adipose or neural tissues will find this polyclonal antibody a versatile tool for both qualitative and semi-quantitative detection across the recommended immunoassays.