Anti-α-SMA Antibody

Recombinant rabbit monoclonal antibody raised against alpha-smooth muscle actin (α-SMA), supplied by Antibodies.com as a 100 µl liquid preparation in TBS (pH 7.4) with 1% BSA, 40% glycerol, and 0.05% sodium azide as preservative. The unconjugated primary antibody is validated for western blot, immunohistochemistry, and flow cytometry, and shows reactivity across human, mouse, rat, and zebrafish samples, supporting cross-species work in vascular biology, fibrosis modeling, and myofibroblast characterization.

α-SMA is a widely used cytoskeletal marker for smooth muscle cell differentiation, activated myofibroblasts, and stromal remodeling within the tumor microenvironment. Researchers apply this reagent to fixed-tissue staining of liver, kidney, and lung sections to assess organ fibrosis, to wound-healing models tracking granulation tissue, and to protein lysate analysis of contractile phenotypes in cell-culture systems. The recombinant monoclonal format is intended for research use only and is delivered in a vial format suitable for aliquoting into smaller working volumes.