All-Trans Retinoic Acid, 500 mg

A research-grade laboratory chemical supplied by STEMCELL Technologies, this product is a crystalline solid preparation of all-trans retinoic acid, also known as ATRA, retinoic acid, trans retinoic acid, tretinoin, vitamin A acid, or NSC 122758. The substance is the sole component, present at 100% by weight, and is identified by CAS No. 302-79-4, with the systematic chemical name (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohexen-1-yl)nona-2,4,6,8-tetraenoic acid, a molecular formula of C20H28O2, and a molecular weight of 300.4.

Solubility is reported as ~0.5 mg/mL in EtOH and ~20 mg/mL in DMF and DMSO. The chemical is classified under the 2012 OSHA Hazard Communication Standard as a Category 2 skin irritant and a Category 1B reproductive toxicant, with hazard statements that it causes skin irritation and may damage fertility or the unborn child, and it is described as very toxic to aquatic life with long lasting effects. It is stable under normal conditions, is intended for laboratory/research use only and not for human or animal diagnostic or therapeutic uses, should be stored locked up in tightly closed containers in a dry, cool and well-ventilated place, and should be kept away from strong acids, strong bases, and strong oxidizing agents.