Tropomyosin Antigen >90%

Tropomyosin is a coiled-coil dimeric protein that associates along the length of actin filaments in muscle and non-muscle cells, where it regulates the calcium-dependent interaction between actin and myosin during contraction. This Tropomyosin Antigen from Antibodies.com is supplied as a liquid preparation at greater than 90% purity and is intended for research use only, making it suitable for use as a coating antigen or immunogen in immunoassay development, antibody characterization, and standardization workflows.

The target is well studied in allergy research: tropomyosin is a pan-allergen recognized across invertebrate species, including the major shellfish allergen Pen a 1 from shrimp, the house dust mite allergen Der p 10, and the Anisakis allergen Ani s 3. Because IgE-binding epitopes are largely conserved among these sources, the antigen is frequently used to investigate cross-reactivity patterns, validate species-specific antibody panels, and support component-resolved diagnostics. Researchers also employ purified tropomyosin as a positive control in western blot and ELISA workflows when screening sera or hybridoma supernatants for anti-tropomyosin reactivity, and as a reference standard when calibrating house-made allergen extracts. The 100 µg pack size provides ample material for multiple assay setups, and the liquid format reduces hands-on preparation time compared with lyophilized alternatives.