Pepsinogen I (PGI) Antigen >90%

Purified native Pepsinogen I zymogen preparation for use as an immunogen or assay standard in gastric function research. This lyophilized antigen from Antibodies.com is supplied at >90% purity and is validated for ELISA and Western blot workflows, supporting reproducible detection of the chief-cell secreted precursor in studies of atrophic gastritis and gastric cancer screening.

Pepsinogen I (PGI) is synthesized by gastric chief cells and converted to pepsin under acidic conditions; its circulating level serves as a non-invasive marker of gastric mucosal integrity. Each vial contains 100 µg of lyophilized material that reconstitutes readily for coating plates or running SDS-PAGE. The preparation's >90% purity reduces background interference in immunoassays, making it appropriate for antibody pairing, calibration curve generation, and standard-spike recovery experiments in research use only protocols.