Myeloperoxidase (MPO) Antigen >95%

Purified myeloperoxidase (MPO) antigen prepared at greater than 95% purity, supplied as a 1 mg liquid format suitable for immunoassay development and antibody validation workflows. MPO is a heme-containing peroxidase abundantly stored in neutrophil azurophilic granules, where it catalyzes the conversion of hydrogen chloride and hydrogen peroxide into hypochlorous acid during the respiratory burst.

This Antibodies.com antigen is affinity purified and validated for ELISA and western blot applications, supporting studies of neutrophil activation, cardiovascular inflammation, sepsis biomarkers, and oxidative tissue injury. Researchers can use the antigen as an immunogen, as a coating reagent for standard curves, or as a positive control on western blots when probing patient samples or cell lysates for endogenous MPO expression.

The liquid formulation simplifies dilution into assay buffers for research use only, and the high purity minimizes cross-contamination from granule co-resident proteins such as elastase, cathepsin G, or lactoferrin, helping investigators attribute signal in their assays specifically to MPO rather than to contaminating neutrophil granule content.