Human Thyroid Stimulating Hormone Receptor (Active)

Supplied by Antibodies.com as a 100 µg liquid format, the Human Thyroid Stimulating Hormone Receptor (TSHR) active protein is used in receptor binding assays, cAMP signaling studies, and autoimmune thyroid research. TSHR is a seven-transmembrane G-protein coupled receptor (GPCR) expressed on thyroid follicular cells, where it transduces TSH binding into Gαs-mediated cAMP accumulation. The active preparation retains native conformational epitopes critical for ligand recognition, making it relevant for studies of Graves' disease, congenital hypothyroidism, and TSHR autoantibody characterization. Recommended storage is at -20°C in working aliquots, with protection from repeated freeze-thaw cycles. For research use only.