Human Keratinocyte Growth Factor 2 (Active)

Human Keratinocyte Growth Factor 2 (KGF-2), also designated FGF-10, is a recombinant bioactive protein that functions as a paracrine mediator of epithelial-mesenchymal signaling. Supplied by Antibodies.com as a lyophilized preparation of 100 µg, this unconjugated product is formulated for research-grade cell culture and downstream signaling studies.

FGF-10 signals selectively through the FGFR2b receptor isoform expressed on epithelial cells, stimulating keratinocyte proliferation, lung epithelial branching morphogenesis, and tissue repair processes. The protein supports dermal regeneration research, mucosal healing models, and organoid differentiation protocols. Reconstitute the lyophilized powder in sterile buffer, aliquot into single-use portions, and store frozen at -20°C to -80°C; limit repeated freeze-thaw cycles to preserve mitogenic activity.

Typical applications include primary keratinocyte expansion, airway and intestinal organoid establishment, proliferation assays, and FGFR2b-MAPK signaling analysis. Each vial is supplied with lot-specific quality-control data confirming consistent bioactivity in mitogenic cell-based assays.