Human Interleukin 10 (Active)

Recombinant human Interleukin-10 (IL-10), also known as Cytokine Synthesis Inhibitory Factor (CSIF), is a pleiotropic anti-inflammatory cytokine secreted by monocytes, macrophages, T helper 2 cells, and regulatory B cells. This biologically active preparation from Antibodies.com is supplied as a 10 µg lyophilized powder in a sealed vial and can be reconstituted in sterile deionized water or a suitable buffer before use.

The protein functions as a potent immunosuppressant, inhibiting the production of pro-inflammatory mediators such as IFN-gamma, TNF-alpha, IL-1 beta, and IL-6, while supporting B-cell proliferation and antibody class switching. Typical research applications include in vitro cell culture, T-cell differentiation studies, macrophage polarization assays, STAT3 phosphorylation analysis, and inflammation or autoimmune disease modelling in immunology workflows.

For long-term stability, store the lyophilized material at -20 °C or below, protected from light. After reconstitution, aliquot into single-use portions to limit repeated freeze-thaw cycles and keep working aliquots refrigerated. The reagent is intended for research use only in laboratory settings.