Human Interferon alpha 2b (Active)

Human Interferon alpha 2b (IFN-α2b) is a recombinant type I interferon cytokine supplied by Antibodies.com as a biologically active, unconjugated lyophilized preparation. The 19.3 kDa protein engages the IFNAR1/IFNAR2 receptor complex and activates the canonical JAK-STAT signaling cascade, driving expression of interferon-stimulated genes (ISGs) that establish an antiviral state. Researchers apply IFN-α2b in cell culture to interrogate innate immunity, characterize viral restriction factors, and model antiproliferative responses in oncology and fibrosis studies.

This 100 µg vial is lyophilized for long-term stability and is typically reconstituted in sterile deionized water before dilution into culture medium or assay buffer. Store refrigerated for short-term use; for extended storage keep frozen and aliquot reconstituted stocks into single-use vials to limit freeze-thaw cycles. The reagent retains activity across standard in vitro bioassay formats, including cytopathic effect (CPE) inhibition, reporter-based ISG induction, and antiviral plaque reduction assays, providing a reliable reference standard for interferon signaling and host-pathogen research.