Human Interferon alpha 1b (Active)

The recombinant Human Interferon alpha 1b (IFN-α1b) Active protein supplied by Antibodies.com is a biologically active, single-chain type I interferon cytokine of 166 amino acids (approximately 19.4 kDa). The lyophilized 100 µg vial format preserves native antiviral, antiproliferative, and immunomodulatory activity upon reconstitution.

Mechanistically, the protein engages the heterodimeric IFNAR1/IFNAR2 receptor complex on target cells, triggering JAK-STAT signaling and induction of interferon-stimulated genes (ISGs). Researchers commonly deploy this reagent in cell-based bioactivity assays, antiviral protection studies, receptor-binding investigations, and as a quantitative standard in ELISA and western blot workflows that measure type I interferon responses.

For handling, store the lyophilized powder at -20°C; aliquot after reconstitution in sterile buffer and keep frozen to limit freeze-thaw cycles. Protect from light during use. The product is for research use only and supports studies in virology, oncology, immunology, and inflammation.