Human Cytokeratin 19 (Active)

The Human Cytokeratin 19 (Active) protein from Antibodies.com is a full-length, biologically active recombinant preparation widely used in epithelial biology research. Cytokeratin 19 (KRT19) is a type I intermediate filament protein with a molecular mass of approximately 40 kDa, and it is one of the smallest members of the keratin family. The protein is expressed in simple and stratified epithelia and serves as a recognized marker of epithelial differentiation.

This preparation is supplied as a liquid in a single-use vial at 100 µg per unit and is unconjugated, compatible with custom labeling workflows. Researchers commonly apply active Cytokeratin 19 in immunohistochemistry, western blot analysis, ELISA, flow cytometry, and in vitro epithelial cell culture studies. The protein is also referenced in studies of circulating tumor cells, breast cancer prognosis, gastric carcinoma, and epithelial-mesenchymal transition (EMT).

For optimal stability, store the protein at -20 °C in working aliquots to limit freeze-thaw cycles. Handle on ice and protect from light where applicable to preserve activity. This research-use-only reagent is intended for laboratory investigation of keratin network assembly, epithelial cytoskeleton function, and tumor biomarker development.