Diphenhydramine-BSA Antigen

Liquid antigen conjugate from Antibodies.com built to direct immune responses against diphenhydramine, a first-generation ethanolamine-class antihistamine. In this preparation the small drug molecule is covalently coupled through an available amine to lysine residues on bovine serum albumin (BSA), raising the apparent molecular weight and exposing new epitopes so the hapten becomes visible to B cells in immunized hosts such as rabbits, goats, or mice. Polyclonal or monoclonal antibodies generated against this diphenhydramine-BSA immunogen are core reagents for competitive immunoassay workflows used in drug monitoring, pharmacokinetic studies, forensic toxicology screening, and pharmaceutical quality-control pipelines. The BSA scaffold additionally stabilizes the conjugate in aqueous buffer and provides carboxyl and amine handles for further crosslinking if a secondary reporter or solid-phase linkage is required. The product ships as a liquid BSA-hapten conjugate at 1 mg per vial, supplied ready to dilute into PBS for host immunization schedules or to adsorb directly onto microplate wells during assay development. For handling, aliquot upon first thaw to limit repeated freeze-thaw exposure, store frozen at -20 degrees C in working volumes, and protect from light. Intended for research use only, not for diagnostic or therapeutic application.