Dengue Virus (DENV-Env Serotype 1) Ag ≥95%

Recombinant Dengue Virus serotype 1 envelope glycoprotein ectodomain, affinity purified to ≥95% homogeneity and supplied by Antibodies.com as a 100 µg vial of ready-to-use antigen. The ectodomain construct exposes the immunodominant epitopes of the E protein, the principal target of virus-neutralizing antibodies generated during natural DENV infection, making this reagent a strong candidate for use as an Immunogen in antibody development campaigns and as a coating reagent in ELISA assays.

Each preparation is derived from recombinant expression and purified by affinity chromatography, minimizing contamination from host-cell proteins and allowing reproducible signal generation in downstream binding and immunoassays. Researchers working on flavivirus diagnostics, vaccine antigen screening, and serological surveillance rely on serotype-resolved E antigens to characterize binding profiles and to standardize assay calibrators. Handling should follow standard biosafety precautions appropriate for a Risk Group 2 pathogen derivative, and the product is intended for research use only.

For antigen-coating protocols, brief dilution in PBS or carbonate buffer at working concentrations determined empirically for each assay system is recommended. Storage at -20 °C or below preserves activity; aliquoting upon first use avoids repeated freeze-thaw cycles that can degrade the ectodomain. Antibodies.com provides technical documentation and lot-specific certificates of analysis to support reproducible experimental setup across lots.