Chlamydia trachomatis (MOMP) Antigen

Recombinant Chlamydia trachomatis major outer membrane protein (MOMP) antigen supplied by Antibodies.com as a 100 µg liquid preparation for immunoassay development, vaccine research, and serological studies. MOMP is the dominant surface-exposed protein of C. trachomatis elementary and reticulate bodies, encoding four variable domains (VD1–VD4) that define serovar specificity across the trachoma, urogenital, and lymphogranuloma venereum biovars.

Researchers employ this antigen as an immunogen for polyclonal and monoclonal antibody generation, as a plate-bound coating protein for ELISA and immunofluorescence protocols, and as a reference standard in western blot characterization of patient sera. The liquid format is aliquoted for single-use applications to limit freeze-thaw cycles and preserve the conformational epitopes recognized by neutralizing antibodies.

Storage at -20 °C is recommended; the product should be protected from light and handled with appropriate biosafety practices given the bacterial origin. Each vial contains 100 µg of purified protein with a molecular weight near 40 kDa, suitable as a positive control in diagnostic assay validation and as a screening reagent for chlamydial vaccine candidate evaluation. Use of well-characterized MOMP preparations from Antibodies.com supports reproducible data across comparative studies of ocular trachoma, genital chlamydia pathogenesis, and serovar epidemiology.