Borrelia burgdorferi Antigen

Whole-cell spirochete preparations are essential reagents for Lyme disease research, and this 1 mg Borrelia burgdorferi antigen from Antibodies.com delivers intact organisms harvested from growth medium and washed in phosphate-buffered saline (PBS). Retaining the native outer-surface lipoproteins and inner-membrane proteins gives researchers access to the full antigenic profile rather than a single recombinant target.

Typical laboratory applications include coating microplate wells for ELISA-based serology, running Western blot confirmation assays, preparing positive-control slides for immunohistochemistry, and immunizing host animals to raise polyclonal or monoclonal antibodies against B. burgdorferi epitopes. The PBS-washed format reduces carry-over of medium components that could introduce background in downstream immunoassays.

Each vial contains 1 mg of wet-organism pellet equivalent, intended for research use only. The reagent supports investigations into spirochete pathogenesis, tick-borne disease diagnostics, and vaccine antigen discovery.