Cancer Antigen 15-3 (CA 15-3) MUC 1 Antigen

Supplied through Antibodies.com as a native, liquid-format antigen preparation derived from a human carcinoma cell line, this MUC1 protein (Cancer Antigen 15-3 / CA 15-3, Breast carcinoma-associated antigen DF3, CD227, Mucin-1) is offered in a 10 kU pack size and is intended for research use only. The purified material migrates at a predicted molecular weight of approximately 400 kDa and is supplied at greater than 60% purity in 50 mM sodium phosphate buffer (pH 7.5) containing 150 mM sodium chloride and 0.09% sodium azide; the concentration is reported as lot-specific. Storage guidance from the supplier recommends shipment at 4 °C, short-term storage at 4 °C for up to one week, and long-term storage at –20 °C while avoiding repeated freeze/thaw cycles. The reagent is commonly deployed in immunoassay workflows — including ELISA — as a calibrator or standard for breast-cancer-associated CA 15-3 quantitation, alongside the established synonym set CA 15-3, Cancer antigen 15-3, Carcinoma-associated mucin, Episialin, H23AG, PUM, and the broader MUC1/KL-6/MAM6 family. Because the molecule is presented in its native, full-length conformation rather than as a tagged recombinant construct, the preparation preserves the heavily O-glycosylated mucin epitopes — including the DF3 peptide core recognised by the CA 15-3 and CA 27.29 monoclonal antibody pair used clinically to monitor breast cancer — making it suitable as both an immunoassay reference and a control antigen in serological CA 15-3 studies.