Zolpidem-HRP Antigen

Conjugated antigen reagent from Antibodies.com for the immunodetection of zolpidem, a non-benzodiazepine imidazopyridine sedative prescribed for short-term insomnia management and monitored in clinical, forensic, and workplace drug-testing programs. The zolpidem target is covalently linked to horseradish peroxidase (HRP), producing a tracer that supports competitive immunoassay workflows in which labeled drug competes with free drug in the sample for antibody binding sites.

Supplied as a 1 ml liquid preparation in an enzyme-stabilizing diluent that preserves peroxidase activity through repeated freeze-thaw handling when aliquoted and held at -20 °C, protected from light. Researchers use this reagent to establish standard curves in microplate assays, to characterize anti-zolpidem antibody specificity during assay development, and to investigate cross-reactivity with structurally related imidazopyridines including alpidem and the principal metabolites zolpidem 6-carboxylic acid and zolpidem phenyl-4-carboxylic acid.

Routine applications include toxicology screening of urine and oral fluid, pharmacokinetic profiling, and antibody-pair screening for in vitro research use only. Each vial provides sufficient tracer for hundreds of microplate wells at typical working dilutions, supporting high-throughput screening panels covering sedative-hypnotic compounds.