Mouse Interleukin-17A ELISA Kit

Profiling of the pro-inflammatory cytokine interleukin-17A (IL-17A) in mouse model systems is supported by this 192-test ELISA microplate kit from Antibodies.com. IL-17A, secreted principally by Th17 CD4+ T cells and type 3 innate lymphoid cell populations, orchestrates neutrophil recruitment, mucosal barrier defense, and chronic inflammatory cascades central to murine models of psoriasis-like dermatitis, rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. The assay accommodates quantitative work in serum samples, plasma samples, and conditioned media harvested from cultured mouse splenocytes or peripheral blood mononuclear cells, suiting studies of Th17 polarization kinetics, vaccine immunogenicity, and candidate-therapeutic screening against the IL-23/IL-17 signaling axis. Each kit supplies the principal immunoassay components: a pre-coated microwell strip plate, biotinylated detection reagent, streptavidin-conjugated enzyme reporter, calibrated recombinant IL-17A standard, wash concentrate, and chromogenic substrate. Reagents are formatted for two full plate runs, distributed across individual vials sized for repeated use, and intended for research use only, not for clinical diagnostic application.