Human beta 2 Microglobulin ELISA Kit

Manufactured by Antibodies.com for the quantitative measurement of beta 2 microglobulin (B2M), this 96-test microplate-format immunoassay enables researchers to investigate a clinically important low-molecular-weight protein in human-derived samples. Beta 2 microglobulin is an 11.8 kDa polypeptide that non-covalently associates with the heavy chain of MHC class I molecules and is constitutively expressed on virtually all nucleated cells, with measurable levels shed into the circulation. Circulating B2M concentrations serve as a research biomarker for renal tubular dysfunction, correlate with tumor burden in multiple myeloma and non-Hodgkin lymphoma, and rise during immune activation in chronic viral infection and transplant rejection studies. The kit includes pre-coated microplate wells, calibrated standards, biotinylated detection reagent, streptavidin-HRP conjugate, wash buffer, substrate solution, and stop reagent, along with a protocol sufficient for 96 individual determinations. Intended for in vitro research use only, the assay supports translational research, biomarker validation, and immunology laboratory workflows involving cell culture supernatant and other human sample types.