CASP3 antibody, 0.7mg/ml

CASP3 antibody, 0.7mg/ml — CASP3 (caspase-3) antibody provided at 0.7 mg/mL in a 100 µL liquid format; enhanced from the original brief description to include intended uses, handling, and manufacturer details.

Manufacturer: MOLEQULE-ON, New Zealand. Supplier: EMDA.

• Target & research context: Detects caspase-3 (CASP3), a key executioner protease in programmed cell death widely used as an apoptosis marker in cell and tissue studies.
• Typical applications: Commonly used for Western blot, immunohistochemistry, immunofluorescence, immunoprecipitation, and flow cytometry assays to monitor caspase-3 expression or activation in research models.
• Important specificity note: Antibodies against caspase-3 may detect the full-length zymogen (approx. 32–35 kDa), the cleaved active fragments (~17 kDa/12 kDa), or both—verify the product datasheet for epitope/cleaved-form specificity before experimental design. Induction of apoptosis is typically required to detect cleaved (active) caspase-3.
• Handling & storage: Store long-term at ≤-20°C, aliquot to avoid freeze-thaw cycles, and follow the manufacturer's datasheet for shipping and short-term storage recommendations.
• Use cases / value: Recommended for apoptosis pathway studies, drug/compound screens that modulate cell death, validation of apoptotic markers in treated cell lines or tissue sections, and quantitative assays when combined with appropriate controls and positive induction.

Note: This description enhances the original product line (CASP3 antibody, 0.7mg/ml) with specifications, common features, and recommended best practices. Consult the manufacturer (MOLEQULE-ON) datasheet or technical support for antibody host, clonality, validated species reactivity, and recommended dilutions for each application prior to use.