SB431542, 25 mg

SB431542, 25 mg — A selective inhibitor of the TGF-β type I receptor kinases (ALK4/5/7) commonly used to block SMAD2/3 phosphorylation in cell-based studies. Supplied by STEMCELL Technologies for research applications, this small molecule is used to modulate TGF-β signaling in stem cell differentiation and fibrosis models.

• Manufacturer: STEMCELL Technologies
• Handling: dissolve in DMSO, store desiccated at -20°C and protect from light
• Application notes: typically used at low micromolar concentrations in cell assays; refer to literature for assay-specific conditions
• For research use only. Not for human or clinical use.