Neomycin sulfate, CAS # 1405-10-3

Neomycin sulfate, CAS # 1405-10-3 — Neomycin sulfate is an aminoglycoside antibiotic provided here in a 10g pack. Manufacturer: MOLECULE-ON (New Zealand). Supplier: EMDA. This entry enhances the existing description with key specifications, uses and handling guidance while preserving the original identifier.

Key specifications: white to slightly yellow hygroscopic powder; highly water-soluble (stock solutions commonly prepared at tens of mg/mL); molecular weight for the sulfate salt is reported ~908.9 but may vary with hydration state — confirm batch CoA for exact value. Recommended storage: cool, protected from moisture (typical storage 2-8°C); prepare filter-sterilized stock solutions and aliquot to avoid repeated freeze/thaw. (chemicalbook.com)

Mode of action & spectrum: an aminoglycoside that binds bacterial ribosomal RNA (small subunit) and inhibits protein synthesis; active primarily against many gram-negative organisms and some gram-positive species. Common formulation uses include topical creams, ophthalmic and otic preparations and oral preparations for gut decontamination in specific clinical contexts. (mpbio.com)

Laboratory & application notes: frequently used in research and manufacturing for formulation or as an antimicrobial additive; prepare stock concentrations according to solubility and label MW, store aliquots at recommended temperatures, and follow aseptic handling. See batch CoA/SDS for purity and assay information prior to use in sensitive assays. (glpbio.com)

Safety summary: not recommended for systemic administration without clinical oversight due to known nephrotoxicity and ototoxicity risks; handle with appropriate PPE, avoid inhalation and skin contact, and consult the product SDS for disposal and emergency measures. For human therapeutic use follow regulatory and pharmacopeial guidance; this material may be sold for research or manufacturing use only depending on supplier labeling. (chemicalbook.com)