MOLEQULE-ON, New Zealand
Human BMP 2
Human BMP 2
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Recombinant Human BMP 2 — Recombinant Human BMP 2 is a research-grade bone morphogenetic growth factor (TGF-β family) that enhances osteogenic and chondrogenic differentiation in vitro and is widely used in bone-regeneration, tissue-engineering, and stem-cell differentiation assays. (ptglab.com)
Manufacturer: MOLEQULE-ON (New Zealand). Supplier: EMDA. For lot-specific details (expression host, specific activity, and endotoxin) consult the Certificate of Analysis supplied with each vial.
- Size: 10 µg (lyophilized).
- Active form / molecular mass: biologically active as a disulfide-linked homodimer (~26 kDa non-reduced; ~13 kDa monomer; mature monomer ~115 aa). (prospecbio.com)
- Typical working range: commonly used at 20–50 ng/mL for in vitro differentiation assays (ED50/ALP induction varies by cell line and preparation). (cellsignal.com)
- Formulation & handling: supplied lyophilized; reconstitute in a small volume of sterile acidic buffer (e.g., 4 mM HCl or 20 mM acetic acid) and include 0.1% BSA/HSA as a carrier for long-term stability; aliquot and avoid repeated freeze-thaw. Confirm recommended reconstitution in the lot COA. (thermofisher.com)
- Applications: osteogenesis and chondrogenesis assays, alkaline phosphatase (ALP) induction, stem cell lineage specification, biomaterials/coating for bone-regeneration models and in vitro potency testing. (stemcell.com)
Features & benefits: potent and well-characterized osteoinductive activity for reproducible differentiation studies; compact, research-grade format for laboratory use; manufacturer MOLEQULE-ON provides batch documentation—review COA before use.
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